When using a CNC vertical lathe for the first time, there are several important aspects to note:

1. Learning and familiarity with the operation: Before starting to operate the CNC vertical lathe, make sure that you are familiar with the operation manual of the machine tool and the relevant safety regulations. For those who use CNC vertical lathes for the first time, it is best to receive professional training or seek the guidance of experienced operators.
2. Safe operation: Make sure you understand and abide by relevant safety operating procedures and safety measures. This includes wearing personal protective equipment correctly, understanding emergency stop controls, knowing where the emergency stop button is located, becoming familiar with emergency stop procedures, etc.
3. Check machine tools and tools: Before using the CNC vertical lathe, check the machine tools and tools to ensure that they are in good working condition. Check the wear and stability of the tool, check the tightness of the bolts and nuts, etc.
4. Writing and importing programs: Familiar with CNC programming language, and write appropriate processing programs. Make sure the program is correct and import it into the CNC. If you are a beginner or not very familiar with programming, you can ask a professional to write a program.
5. Make equipment settings: according to the processing requirements, make appropriate equipment settings, including fixing workpieces and tools, setting cutting parameters, and setting processing paths.
6. Observation and adjustment: Before starting processing, observe the operation of machine tools and tools to ensure that everything is normal. Make necessary adjustments and corrections, if necessary.
7. Monitor the processing process: when the processing process starts, regularly monitor the operation status and processing quality during the processing process. If there is any abnormal situation, take corresponding measures immediately to ensure safe and normal processing.

Keep in mind that these are just suggestions and that the exact procedure may vary depending on the machine model, machining task and personal experience. Always refer to the operator's manual and related resources and follow professional safety advice before using any machine tool.